Microsoft word - fidka bio true web version august 2009.doc

Felix I D Konotey-Ahulu FGA
Dr Kwegyir Aggrey Distinguished Professor of Human Genetics, University of
Cape Coast, Ghana and Consultant Physician Genetic Counsellor in Sickle Cell
and Other Haemoglobinopathies, 10 Harley Street, London W1G 9PF, England.

Name: Felix Israel Domeno Konotey-Ahulu
Place of Birth: Odumase-Krobo, Ghana
Key Achievements: National and International Awards
(1) 1972 in Philadelphia "Dr Martin Luther King Jr Foundation Award for
"outstanding research in Sickle Cell Anaemia". Konotey-Ahulu was invited to deliver the Keynote Address. Also honoured were Nobel Laureates Linus Pauling and Max Perutz, with Roland Scott, Hermann Lehmann, A C Allison, J V Neel, Graham Serjeant, James Boweman & others. (2) 1974 Accra, Gold Medal of Ghana Academy of Arts & Sciences for "the most
outstanding contribution to knowledge in the Medical Sciences by a Ghanaian between 1952 and 1973". (3) 1976 London. Guinness Award for Scientific Achievement (GASA) in the
Commonwealth for "his work in applying science to the service of the community". (4) 1999 Senegal, Dakar. President Diouf presented him with the 1998 Third World
Academy of Sciences (TWAS) Award in Basic Medical Sciences "for
outstanding contributions to haemoglobinopathy and Clinical Medicine, and
advocating ethical dimensions for genetic programmes, and highlighting public
health measures as the best tool for long-term sickle cell patient management".
(5) 2000 University of Cape Coast, Ghana. Awarded Doctor of Science (DSc Honoris
Causa), and a Personal Chair, ‘Dr Kwegyir Aggrey Distinguished Professor of Human Genetics'. (6) 2007 African American Museum In Philadelphia [AAMP] Humanitarian Award
"presented in recognition of your distinguished service and exceptional contributions to the people of Africa and to the world". Lecture: "The Remarkable African Ear: Phenomenon of Mid Pitch Arrest in Krobo/Dangme-Gã Tonal Languages of South East Ghana", May 5. (7) 2007 Award Citation for Meritorious Service presented by Nene Sakite II, Konor of
Manya Krobo who conferred on him the title "Klo HingmεThe Eye of Krobo"
after Ghana@50 Lecture on Tonal Linguistics, Ghana Academy of Arts &
Sciences, Accra, 30th October 2007.
(8) 2008 Ghana National Award by President J A Kufuor ORDER OF THE VOLTA –
OFFICER "for distinguishing yourself in MEDICINE/RESEARCH INTO SICKLE
(9) 2008 University of Ghana awards him LEGON HALL DISTINGUISHED ALUMNI
(1) Felix Konotey-Ahulu is the first person known to have traced hereditary disease in his forebears, generation by generation, with all names, right back to 1670
AD Not been done
(2) Haemoglobin Korle Bu, the first example of intra-genic cross-over was the
discovery of Konotey-Ahulu and collaborators] Konotey-Ahulu FID, Gallo E, Lehmann H, Ringelhann B. Hemoglobin Korle Bu (α2β2 73 Aspartic Acid  Asparagine), showing one of the two amino acid substitutions of Haemoglobin C Harlem Journal of Medical Genetics 1968 Vol 5 pp 107 -111] See Publication 11. (3) Konotey-Ahulu F I D, Kinderlerer JL, Lehmann H, Ringelhann B. Haemoglobin
Osu-Christiansborg. A new beta-chain variant of Haemoglobin A (52 D3
Aspartic Acid  Asparagine in combination with Haemoglobin S.
Jour.Med.Genet 1971. Vol 8, pp 302-305 [Publication 28].
(4) The numb lower lip sign of sickle cell crisis. Konotey-Ahulu FID, in Lancet
1972 Vol 2, p38 "Mental nerve neuropathy: a complication of sickle-cell crisis" See Publication 43. (5) Audible Parkinsonian tremor. Konotey-Ahulu F I D. Lancet 1968, Vol1, p 752
[Been called ‘Kaps sign' – Konotey-Ahulu Parkinsonian Stethoscope Sign]. See Publications vi, 214, & 235. (6) ‘Gnathopathy' a word Konotey-Ahulu coined in Clinical Medicine to describe a
maxillary physical sign which he graded ‘1', ‘2', ‘3' Archives of Internal Medicine 1974, Volume 133, pages 611 – 619. [Publication 51] Konotey-Ahulu invented a mathematical Index for Population Genetics.
Published in the British Medical Journal 1980, Vol 281, pp 1700-1702 "Male
procreative superiority index (MPSI): The missing coefficient in African
". [Publication 92]
(8) African Tonal Language Discovery: Konotey-Ahulu has described an African tribe (his own Krobo/Dangme) where everybody has perfect mid-pitch. They
isolate mid-pitch, and assign it to particular words. "Mother tongue: Introducing
the Tadka Phonation Technique For Speaking An African Tonal Language
Krobo/Dangme-Ga of South-East Ghana
" T-A'D Co 2001 UK ISBN: 0-
9515442-4-1. Not described before in Tonal Linguistics. [Pubs. 164 & 238]
(9) He invented the kanad for genetic counselling [See illustration below]
Family History: Born second of 11 children of Rev David Andrews Konotey-Ahulu
and Mrs Christiana Mamle Okleyo Konotey-Ahulu (née Matekole). See Genealogy
back to 1670 AD in Married in
1962 to Rosemary Moss - 1 son and 2 daughters, and 11 grandchildren.
Education & Qualifications: Achimota Kindergarten 1935; Presbyterian Schools
1936-1946; Achimota School 1947-1949 Cambridge School Certificate Grade 1 &
London Matriculation 1st Division; Mfantsipim Pre-University (Picot Hall) 1950-1951;
University College of the Gold Coast (Legon Hall) 1952-1953; Norwood Technical
College 1953-1954; University Col ege London 1954-1956 (2nd MB); Westminster
Hospital School of Medicine 1956-1959 MRCS LRCP & MB BS(London); Liverpool
School Tropical Medicine DTM&H 1962; Hammersmith Hospital Postgraduate
School of Medicine 1962; Westminster Hospital Postgraduate 1963; Royal Free
Hospital Department of Medicine 1964-65 MRCP (Glasgow), MRCP (London);
Christ's College Cambridge University Schofield Postgraduate Fellow 1970-71 FRCP
; London University MD (Doctorate in Medicine) 1972; Royal College of
Physicians London FRCP (London) 1975. DSc UCC conferred 2000.
Work & Life Activities: Post-registration House Jobs in Medicine (London, Bethnal
Green Hospital) June–Dec 1959 and Surgery (St Albans City Hospital Jan–June
1960); Medical Officer Ministry of Health Ghana at Korle Bu Hospital July 1960 - Dec
1961); Physician Specialist Korle Bu Hospital 1965-1979; Lecturer/Senior Lecturer
University of Ghana Medical School 1965-1972; Appointed Honorary Consultant to
the Ghanaian Ministry of Health by Brigadier General Odartey-Wellington,
Commissioner of Health 1976; Director Ghana Institute of Clinical Genetics
[Managing Trustees of VALCO FUND & Ministry of Health] at Korle Bu Teaching
Hospital 1973-1979; Pension from Ghana Public Services approved by General Fred
Akuffo on 22nd Feb 1979 to commence 12 July 1979 [Ghana Pensioner No. 118851);
Consultant Physician BUPA Medical Centre London 1979-1983; Consultant
Physician Locum East Ham Memorial Hospital London 1979-1982 and Royal
Northern Hospital for Dr D Geraint James 1983; Consultant Physician Cromwell
Hospital London 1983-2005; Consultant Physician Genetic Counsellor in Sickle Cell
and Other Haemoglobinopathies 10 Harley Street 1979 to date 2009 & 9 Harley
Street November 2008 to date 2009; Dr Kwegyir Aggrey Distinguished Professor of
Human Genetics, University of Cape Coast, Ghana 2000 to date 2009 featuring
Annual Kwegyir Aggrey Prize Exams paid in Guineas.
Some Activities: Was Annual Visiting Professor to Howard University Hospital
Sickle Cell Center Washington DC from 1972 to 1975, and March of Dimes National
Foundation Visiting Lecturer to 11 University Medical Institutions in the USA 1972.
WHO Consultant 1968, 1969, 1970, and invited by WHO Director-General in 1976 "to
serve for a period of five years as a member of the WHO Expert Advisory Panel on
Human Genetics", and extended annually "for a further period of one year".
International Conferences and Lectures including the University of Edinburgh
MacArthur Postgraduate Lecture on Nov 22 1976: "The Sickling Phenomenon:
Historical, Genetic, Clinical and Public Health Considerations", and the University of
Ghana Alumni Lecture, Legon, on 20 March 1980 on the Topic: "Genes and Society,
and Society and Genes". Was the 3rd Editor of Ghana Medical Journal after Professor
Silas R A Dodu and Professor Harold H Phillips.
First to travel through tropical Africa to assess at the grass roots the beginnings of the AIDS epidemic – See Publications of 1987 to 1991 especially Publication 105. Invited to partake in important First Symposia in Human Genetics as shown here:- Invited to contribute: (i) First International Symposium on the Role of Recombinant
DNA in Genetics, Chania, Crete, Greece May 13-16 1985 [Publication 103] (ii) First
& Second International Conferences on The Achievements of Sickle Cell Disease
Patients, Royal Society of Medicine, London 1993, and Accra 1995 [Publications
137a&b (iii) First International Symposium on The Human Genome Diversity Project,
POLITICS and THE LIFE SCIENCES, Lake Superior State University, Sault Sainte
Marie, MI, USA, September 1999 [Publication 154] (iv) History Of Medicine in the
20th Century, Wellcome Trust Witness Seminar on History of Haemodialysis in the
UK, London, 26 February 2008 [Publication 256] (v) First Post Inaugural Symposium,
Howard University National Human Genome Center, Washington DC on "1000
Genomes Project: On The Frontier of Personalised Medicine". Invited Topic: "Global
Genome Sequencing – Some Ethical Considerations" January 23, 2009 [To be
published]. Other participants from Johns Hopkins University and the NIH, Bethesda.

Present Preoccupation: Presently I am occupied with teaching a novel approach to
Genetic Counselling and Voluntary Family Size Limitation [GCVFSL] in Sickle and
other Haemoglobinopathies, not only emphasizing the need for Ethical Principles in
Genetics and Genomics [See Publications], but also involving ‘Patient Achievers' in
the Counselling Process which (using my invented kanad method) ensures that the
message that aims at reducing the burden of sickle cell disease in the next
generation gets through, and can be demonstrated to even lay men and women, and
young students by jointly throwing two dice with the opposite sex. Kanad stands for
‘konotey-ahulu norm ache dice' of six cubes – 2 have ACHE printed on all six sides
in dark red, 2 have NORM printed in green on all six sides, and 2 have NORM and
ACHE alternating on the cube surface. Human phenotypes are NORMNORM, or
NORMACHE or ACHEACHE with respect to beta-globin genes. Felix Konotey-
Ahulu's parents are NORMACHE and NORMACHE. They had 11 children (as stated
above) who shared the phenotypes NORMACHE (4 of us), NORMNORM (4 of us),
and ACHEACHE (3 of us) who suffered hereditary cold-season rheumatism, or
Sickle Cell Disease. Only the ACHEACHE have symptoms. The kanad enables
anyone who knows his/her phenotype to find out which phenotypic pairing will
guarantee a non ACHEACHE offspring [Publications 44, 225, 236, 243, 254]. One in
three Ghanaians is NORMACHE. These do not know they carry an ACHE gene,
because they (like the NORMNORM) are symptom free from hereditary rheumatism,
known as chwechweechwe and other tribal names so they must be identified and
counselled whether abroad, or at home.
Meaningful Genetic Counselling
and Voluntary Family Size Limitation
Health Education in the Mother Tongue: I have developed a novel way of writing African Tonal Languages to facilitate comprehension, especially valuable in Public Health Education in the Mother Tongue – See Publications 164, 218, 238. MILLENNIUM HYMN: I wrote a Millennium Hymn, "TIME WAS CREATED", with 7 verses and Music (Tonic Solfa & Piano) ready for the turn of the Millennium 1999/2000. My hobbies include Piano and Writing. I was involved in founding Accra Chapel in 1967 on the Korle Bu Teaching Hospital compound in Accra, Ghana PUBLICATIONS, INVENTIONS, OTHER OUTPUT:
Of about 300 publications over 46 years listed (xxxvii + 261 + a, b ,c) in none, however brief and insignificant, is without a message. I reproduce about 1 in 3 of these publications below, retaining their numerical position in the original list that can be viewed on line. Where available, the internet identification is given so that they can be down loaded and assessed as to their value in contribution to medical and other knowledge. Notes are added to some in the list of publications for clarification. (1) New African, a popular international monthly based in London, conducted
a 12-month survey of a readership of nearly 200,000 to find who readers thought were "THE ONE HUNDRED GREATEST AFRICANS OF ALL TIME", and why. Published in September 2004, the voters mentioned Felix I D Konotey-Ahulu in the list which had Nelson Mandela, Kwame Nkrumah, Marcus Garvey, Martin Luther King, Kofi Annan, W E B Du Bois, Haile Selassie, Maya Angelou, Gamel Abdel Nasser, Bill Cosby, F W De Klerk, Desmond Tutu, Wole Soyinka, Maheru Mhotep, Abedi Pele, ‘The African Woman', Jomo Kenyatta, Hannibal, to mention some. Konotey-Ahulu asked to be replaced by Dr J E Kwegyir Aggrey about whom he wrote an article for New African ("Aggrey of Africa") published in the Oct 2004 issue, p. 50 to show how altogether greater was Dr Aggrey. [See Publications 174a & 174b]. (2) Professor Helen Ranney MD, Albert Einstein University College of
Medicine, New York, has stated: "There is no single clinical experience in the United States comparable to that of Dr Konotey-Ahulu" [page 320 in SICKLE CELL DISEASE, edited by Abramson/Bertles/Wethers; Mosby Co 1973]. (3) Professor Roland Scott MD, Howard University Centre for Sickle Cell
Disease, Washington DC "This is a meritorious addition to the medical literature and Dr Konotey-Ahulu has been disclosed as a seductive narrator as he tells the story of Sickle Cell Disease" in Foreword, p ix, 1991 ‘The Sickle Cell Disease Patient'. (4) Professor Sir David Weatherall FRS MD FRCP Oxford Univ., in Lancet
June 29 1991, Vol 337 p 1590 "'The Sickle Cell Disease Patient' is a fitting tribute to a physician who has done as much as anyone to improve facilities to deal with this condition in Africa". (5) Professor D Geraint James MA MD FRCP, Royal Free Hospital, London
University, in Sarcoidosis 1992 Vol 9 p 73: "This thesaurus or treasure trove of information adds a new dimension to the world of sickle cell disease". (6) Professor Alastair J Bellingham MB FRCP FRCPath, King's Col ege
Hospital, London University, in Tropical Diseases Bulletin, 1993 Vol 90 No 3, p 164: "This remarkable study must represent the largest compilation and report of a single person's clinical experience … For professionals working within the community and hospital I can recommend it as a marvellous feast to delve into". (7) Dr Maxwell Wintrobe MD PhD, Distinguished Professor of Medicine,
University of Utah, USA in his book Haematology, The Blossoming of a Science – A Story of Inspiration and Effort (Lea & Febriger, Philadelphia) 1985 pp 378-380): "Dr Konotey-Ahulu has contributed to our understanding of the clinical manifestations of sickle cell disease and other haemoglobinopathies in Africa…His contributions are especially noteworthy; the value of his work has been widely recognised". SOCIETIES
Fellow of Ghana Academy of Arts & Sciences; of Ghana College of Physicians and
Surgeons; of African Association of Scientists; of Third World Academy of Sciences;
of Ghana Medical Association; of West African College of Physicians; of Royal
College of Physicians Glasgow; of Royal College of Physicians London; of Royal
Society of Tropical Medicine and Hygiene London; and Member of British Medical
Association; of Royal Society of Medicine; and of Christian Medical Fel owship,
Selected 30% of Publications from 1965 to 2009
Full list of what was published every year since 1965 is
seen at
1. Konotey-Ahulu FID. Sicklaemic human hygrometers. Lancet 1965 May 8;
1(7393): 1003-1004. PMID: 14288540 [PubMed – indexed for MEDLINE]
2. Konotey-Ahulu FID. Torrential epistaxis associated with symmetrical facial skin
ulceration in sickle cell anaemia. BMJ 1965 Oct; 2: 859-860. doi:10.1136/bmj.2.5466.859 [Click here ] PMID: 5827801 [PubMed – indexed for MEDLINE] 3. Konotey-Ahulu FID and Kuma Eunice. Skeletal crumbling in sickle cell anaemia
complicated by Salmonella typhi infection. Brit J Clin Pract 1965 Oct; 19(10):
575-578. PMID: 5830346 [PubMed – indexed for MEDLINE] 4. Konotey-Ahulu FID, Baillod RA, Comty CM, Heron JR, Shaldon S and Thomas
PK. Effect of periodic dialysis on the peripheral neuropathy of end-stage renal failure. BMJ 1965; 2: 1212-1215 (Nov. 20) doi:10.1136/bmj.2.5472.1212 PMID: 4285000 [PubMed - indexed for MEDLINE
11. Konotey-Ahulu FID, Gallo E, Lehmann H and Ringelhann B. Haemoglobin
Korle Bu (alpha2 beta2 73 Aspartic Acid --> Asparagine), showing one of the two amino acid substitutions of Haemoglobin C Harlem. J Med Genet 1968 June; 5(2): 107-111. & An
example of intra-genic cross-over [To download and print
…artid=1468514&blobtype=pdf] PMID: 5722880 [PubMed – indexed for MEDLINE] 14. Konotey-Ahulu FID and Ringelhann B. Sickle-cell anaemia, sickle-cell
thalassaemia, sickle-cell haemoglobin C disease and asymptomatic haemoglobin
C thalassaemia in one Ghanaian family. BMJ 1969 Mar 8; 1(5644): 607-612.
doi:10.1136/bmj-1.5644/607 or PMID: 5766126 [PubMed – indexed for MEDLINE] March 8 1969. 20. Bentsi-Enchill KK, Konotey-Ahulu FID. Thirteen children from twelve
pregnancies in sickle-cell thalassaemia. BMJ 1969 Sep 27; 3(5673): 762
doi:10.1136/bmj.3.5673.762 PMID: 5347184 [PubMed - indexed for MEDLINE] [In Medical Memoranda Sept 27 1969 21. Konotey-Ahulu FID. Maintenance of high sickling rate in Africa: Role of
polygamy. J Trop Med Hyg 1970 Jan; 73(1): 19-21 (38 references). PMID:
4906442 [PubMed – indexed for MEDLINE]

28. Konotey-Ahulu FID, Kinderlerer, JL Lehmann H and Ringelhann B.
Haemoglobin Osu-Christiansborg. A new chain variant of Haemoglobin A (beta 52
D3 Aspartic Acid --> Asparagine) in combination with Haemoglobin S. Journal of
Med Genet 1971 Sep; 8(3): 302-305. or or PMCD: PMC 1469179 & PMID: 5097135 [PubMed – indexed for MEDLINE] 41. Konotey-Ahulu FID. Definition of Sickle cell Trait and Sickle cell Disease.
Ghana Med J 1972; 11:417-420.
43. Konotey-Ahulu FID. Mental nerve neuropathy: a complication of sickle cell
crisis. Lancet 1972 Aug 19; 2(7773): 388 *[Constitutes discovery of a new
physical sign in Clinical Medicine]
xiii. Konotey-Ahulu FID. Sickle cell Trait and Altitude. BMJ 1972; 1(5793): 177-
178. doi:10.1136/bmj.1.5793.177-a (January 15) PMID: 5007853 [PubMed-indexed for MEDLINE 44. Konotey-Ahulu FID. Sickle Cell Disease: The Case for Family Planning. Accra.
ASTAB Books, Ltd 1973; 32 pages.
45. Konotey-Ahulu FID. Effect of environment on sickle cell disease in West
Africa; epidemiologic and clinical considerations. ; Chapter 3 in Sickle-cell Disease
- diagnosis, management, education and research. Eds Abramson H, Bertles FF and Wethers Doris L; St Louis CV Mosby Co 1973 pp 20-38. 51. Konotey-Ahulu FID. The Sickle-cell Diseases: Clinical manifestations including
the Sickle Crisis. Arch Inten Med 1974; 133(4): 611-619. or [PMID: 4818434 [PubMed – indexed for MEDLINE 60. Konotey-Ahulu FID. Polygamy: Effects on Gene Distribution. Chapter 11 in
Interdisciplinary approaches to population Studies. Ed David AS, Laing E and
Addo NO - Legon 1975; pp215-233. Report of Conference 30th November - 4th
62. Archampong EQ and Konotey-Ahulu FID. Biliary tract disease and sickle cell
anaemia in Korle Bu Teaching Hospital, Accra. Ghana Med J 1975 Sep; 14(3):
176-180. PMID: 1234677 [PubMed – indexed for MEDLINE] 70. Bonney GE and Konotey Ahulu FID. Polygamy and genetic equilibrium. Nature
1977; 265: 46-47 (January 6 1977). doi:10.1038/265046a0
…n5589/pdf/265046a0.pdf PMID: 834239 [PubMed – indexed for MEDLINE]
80. Altay C, Ringelhann B, Yawson GI, Bruce-Tagoe AA, Konotey-Ahulu FID,
James L, Gravely M and Huisman THJ. Haemoglobin alpha chain deficiency in
black children with variable quantities of haemoglobin Bart's at birth. Paediatrics
Feb 1977; 11: 147-152. PMID: 840505 [PubMed - indexed for MEDLINE] 84. Mears JG, Ramirez F, Leibowitz D, Nakamura F, Bloom A, Konotey-Ahulu FID
and Bank A. Changes in restricted human cellular DNA fragments containing globin gene sequences in thalassaemias and related disorders. Proc Natl Acad Sci USA 1978 Mar; 75(3):1222-1226. PMID:
274714 [PubMed–indexed for MEDLINE]

85. Bonney GE, Walker M, Gbedemah K and Konotey-Ahulu FID. Multiple births
and visible birth defects in 13000 consecutive deliveries in one Ghanaian hospital. In Proceedings of the Second International Congress on Twin Studies Part C Ed Nance W. Progess in Clinical and Biological Research 1978; 24 Pt B: 105-108.
PMID: 724702 [PubMed – indexed for MEDLINE]
90. Konotey-Ahulu FID. Genes and Society and Society and Genes. Fifth
University of Ghana Alumni Lecture, 20th March 1980, Legon, Ghana.

92. Konotey-Ahulu FID. Male procreative superiority index (MPSI): The missing
co-efficient in African anthropogenetics. BMJ 1980; 281(6256): 1700-1702 doi:10.1136/bmj.281.6256.1700 PMID: 6934845 [PubMed – indexed for MEDLINE] December 20 – 27 1980. 94. Konotey-Ahulu FID. Ethics of amniocentesis and selective abortion for sickle
cell disease. Lancet 1982; 1(8262): 38-39. January 2. PMID: 6119424 [PubMed-
indexed for MEDLINE]
98. Konotey-Ahulu FID. Alpha-thalassaemia nomenclature and abnormal
haepmoglobins. Lancet 1984 May 5; 1(8384): 1024-1025. May 5. PMID:
99. Konotey-Ahulu FID. Ethical issues in prenatal diagnosis. BMJ Clin Res Ed
1984; 289(6438): 185. July 21. doi:10.1136/bmj.289.6438.185-a 6143955
103. Konotey-Ahulu FID. Missing the wood for one genetic tree? The First
International Symposium on the Role of Recombinant DNA in Genetics - Proceedings - Chania, Crete, Greece, May 13-16 1985. Eds Loukopoulos D, Teplitz RL; Athens, P. Paschalidis 1986, pages 105-116. xxxvi. Konotey-Ahulu FID. Points: A boost for clinical research. BMJ April 1986,
page 1081
"If, as I have always thought, the discipline of clinical epidemiology seeks to answer the questions How? Which? When? Who? What? And Where? Are we more likely to get clearer answers in the north to questions relating to the south?" 105. Konotey-Ahulu FID. Clinical epidemiology, not seroepidemiology, is the
answer to Africa's AIDS problem. BMJ (Clin Res Ed) 1987; 294(6587): 1593-
1594 (June 20 1987) doi:10.1136/bmj.294.6587.1593 PMID:3113544 [PubMed
–indexed- for MEDLINE] [This led to 600 reprint requests] 108. Konotey-Ahulu FID. Extensive palatal echymosis from fellatio - a note of
caution with AIDS at large. British Journal of Sexual Medicine 1987; 14: 286-287.
109. Konotey-Ahulu FID. Surgery and risk of AIDS in HIV-positive patients.
Lancet 1987; 2(8568): 1146. November 14. PMID: 2890039 [PubMed-indexed
110. Konotey-Ahulu FID. AIDS in Africa: Misinformation and Disinformation.
Lancet 1987; 2(8552): 206-208. July 25. PMID: 2885651 [PubMed-indexed for
111. Konotey-Ahulu FID. Some thirty features of AIDS in Africa. Annales
Universitaires des Sciences de la Santé 1987
; 4: 541-544.
115. Konotey-Ahulu FID. An African on AIDS in Africa. (Guest Editorial). The
AIDS Letter - Royal Society of Medicine 1989, No 11, Feb/March 1989, pp 1-3.
116. Konotey-Ahulu, FID. What is AIDS? Tetteh-A'Domeno Company, Watford,
England, 1989, 227 pages ISBN: 0 9515442 0 9 117. Konotey-Ahulu, FID. HIV antibody positive sub-Saharan African patients in
UK. Lancet 1990, 335: 46-47. (Response to call from S Murphy et al Nov 18,
p1225 that "all patients who have lived in or worked in sub-Saharan Africa in the past ten years should be offered HIV antibody testing".) PMID 1967347[PubMed-indexed for MEDLINE] 118. Konotey-Ahulu, FID. AIDS in Africa. Policy Review (Heritage Foundation
Publication, Washington DC) Fall 1990; No 54: 78-9. (Invited comment on Professor Peter Duesberg's thesis in the Summer Issue that HIV is not the cause 119. Konotey-Ahulu, FID. The Genetics of Ghanaian High Blood Presssure. Ghana
Medical Journal 1990;
24: 160-163 (Invited Editorial on Dr Jonathan Addy's
discovery that Ghanaian essential hypertension was homozygous recessive inheritance: See Addy JH. Mendellian inheritance of propranolol responsive hypertension in an extended Ghanaian family. Ghana Medical Journal 1990; 24: 164-69 and Addy JH. Genetics of hypertension. Lancet Aug 8 1992 pp 377-378.) 120. Konotey-Ahulu, FID. The AIDS crisis in Africa: a survey. In: Appropriate
Technologies for AIDS Management in Africa Editor Kihumbu Thairu, 3-7 September 1990 Kenya Medical Research Institute, Nairobi. Commonwealth Secretariat London pp 24-27. 121. Quartey JKM, Konotey-Ahulu FID. The domiciliary management of AIDS in a
rural community in Africa. In: Appropriate Technologies for AIDS Management in
Africa Editor Kihumbu Thairu, 3-7 September 1990, Kenya Medical Research Institute, Nairobi. Commonwealth Secretariat London pp 42-44. 122. Konotey-Ahulu, FID. The Sickle Cell Disease Patient. Macmillan Education
Ltd London 1991/1992. Foreword by Roland B Scott, MD (Howard University) - 36
chapters with 4,500 references, 643 pages. ISBN: 0-333-39239-6
123. Konotey-Ahulu, FID. Kwashiorkor. BMJ 1991, 302(6769): 180-181.
(Explaining what this Ghanaian tribal word means) January 19. doi:10.1136/bmj.302.6769.180-c PMID: 1995150 [PubMed-indexed for MEDLINE]
128. Konotey-Ahulu, FID. Beware of symptomatic sickle-cell traits. Lancet 1992;
339(8792): 555. doi:10.1016/0140-6736(92)90377-F PMID: 1346903 [PubMed – indexed for MEDLINE] Feb 29. (Pointing out that the sickle cell trait AS may not be true sickle trait, and the HbC trait AC may be something else, as the "A" has been shown could stand for Hb Quebec-Chori, by Witkowska et al - New Engl J Med 1991; 325: 1150-54.) 134. Konotey-Ahulu FID. Issues in Kwashiorkor. Lancet 1994; 343(8895): 548.
Feb 26. (Commenting on Professor Golden's "We are ignorant about the aetiology
of kwashiorkor" Jan 29, p292, and stressing what the Krobo-Ga-Adangbe tribes people meant when they first took the kwashiorkor toddlers to Dr Cicely Williams in Ghana in 1933). PMID: 7906796 [PubMed-indexed for MEDLINE] 135. Konotey-Ahulu FID. Probing anecdotes in traditional African therapeutics.
African Journal of Health Sciences May 1 1994; 1(2): 53 - 56. PMID: 12153359
[PubMed as supplied by Publisher] 138a. Konotey-Ahulu FID. The Sickle Cell Disease Patient. Watford: Tetteh-
A'Domeno Co, 1996 Reprint of 1991 Macmillan book. ISBN: 0-9515442-2-5
Comments by Professor Roland Scott, Professor Geraint James, Professor Sir David Weatherall, Professor Alastair Bellingham, Professor Helen Ranney, and Distinguisehd Professor Dr Maxwell Wintrobe. 138b. Konotey-Ahulu FID. What Is AIDS? Watford: Tetteh-A'Domeno Co, 1996
Reprint of 1989 book. ISBN: 0-9515442-3-3 with Dr Thomas Mensah's Review.
143. Konotey-Ahulu FID. Valsalva vitreous haemorrhage and retinopathy in sickle
cell haemoglobin C disease. Lancet 1997; 349(9067): 1774. PIMD: 9193406 [PubMed – indexed for
147. Konotey-Ahulu FID. Management of patients with sickle cell disease. African
Journal of Health Sciences
1998; 5: 47[ Commenting on article of Sally Davies
and Lola Oni (BMJ 315: 656 -60) "what I feel is more important in the day to day
management of patients with a view to keeping them out of hospital, is clinical
epidemiology which includes the circumstances of crises. Two examples suffice to illustrate what I mean: . I fear Davies and Oni's statement that ‘The Central Middlesex management protocol uses morphine infusions' will make morphine the accepted drug for sickle crisis management. The consequences of such an approach are dire, especially when some UK hospitals are already making diamorphine their first choice".] 148. Ringelhann B, Konotey-Ahulu FID. Hemoglobinopathies and thalassemias in
Mediterranean areas and in West Africa: Historical and other perspectives 1910
to1997 - A Century Review. Atti dell'Accademia dell Science di Ferrara ( Milan)
1998; 74: 267-307.
149. Konotey-Ahulu FID. Opiates for sickle-cell crisis? Lancet 1998; 351(9113):
1438. May 9. ("The question that puzzles me is: why do west African and West
Indian patients with sickle-cell disease who did without morphine in their
countries have to be given morphine pumps during sickle-cell crises when they come to the UK?") PMID: 9593444 [PubMed-indexed for MEDLINE] 150. Konotey-Ahulu FID. Opiates for sickle-cell crisis. Lancet 1998; 352(9128):
651-652. Aug 22. [Response to David Bevan's criticism (in Lancet 1998; 351: page 1965) of white physicians who agree with Dr Konotey-Ahulu that opiates have created addicts in their hospital - "When I say routine opiates for sickle crisis are not the way to bring out these patients' best potential in the long term I am glad to hear white physicians say the same.White physicians who, at the risk of being misunderstood by Bevan, voice their displeasure at what they see happening on their wards deserve commendation, not condemnation."] PMID:9746049 [PubMed-indexed to MEDLINE] 151. Konotey-Ahulu FID. Supreme worth of clinical epidemiology in Africa:
bancroftian filariasis is just one case in point. African Journal of Health Sciences
1999; 6: 1-2. [Invited Editorial on Dr J O Gyapong's article: Clinical epidemiology
and prospects for control of lymphatic filariasis. African Journal of Health Sciences 1999; 6: 3-8. "Clinical epidemiology is going to be the discipline par excellence of the next century, if not the millennium. Coming as it does from one who has spent decades in Clinical Medicine and Therapeutics, this is a bold statement.Even with the current AIDS problem, I remain convinced that clinical epidemiology is the answer (FIDK-A 1987, Brit Med J Vol 294: pp 1593-94). Vaccines have achieved much this century, but to 'wait for WHO to give us vaccines' while we neglect ourselves and our environment is wholly irresponsible"] 153. Konotey-Ahulu FID. Averting a malaria disaster. Lancet 1999; 354(9174):
258. July 17. [In response to the article in The Lancet 1999, Vol. 353: pp 1965-67 of Professor NJ White and 16 co-authors who argued that in order to avert a malaria disaster, the highly successful Chinese drug Artemisinin should be compounded with other anti-malarial drugs to prevent drug resistance.] PMID: 10421339 [PubMed-indexed for MEDLINE] 154. Konotey-Ahulu FID. The Human Genome Diversity Project: Cogitations of An
African Native. Politics and the Life Sciences (PLS) 1999, Vol 18: No 2, pp 317-
322. [Invited Commentary on Professor David Resnik's article: The Human Genome Diversity Project: Ethical Problems and Solutions.] PMID: 12561789 [PubMed – indexed for MEDLINE] 156. Konotey-Ahulu FID. Black people's red faces and AIDS prevention. Lancet
2000; 355(9214):1559. PMID: 10801206 [PubMed-indexed for MEDLINE]
157. Konotey-Ahulu FID. Public health in less developed countries. Lancet Nov 18 2000;
356(9243): 1769-1770. ["Sarah Macfarlane and colleagues (Lancet 2000; 356: 841-846)
and Robert Beaglehole and Ruth Bonita, in their Sept 2 Commentary ( Lancet 356: 787- 88) omit any mention of the genetic disease burden that will loom ever bigger when AIDS disappears and malaria is rolled back"] PMID: 11095284 [PubMed-indexed for MEDLINE] 161. Konotey-Ahulu FID. The Adult with Sickle Cell Disease. New African Sep. 2001, pp
163. Frimpong-Boateng K, Aniteye E, Amoah AGB, Amuzu VA, Konotey-Ahulu FID. Cardio-
pulmonary by-pass surgery in sickle cell disease: An update. Ghana Medical Journal 2001;
35: 194-197.
164. Konotey-Ahulu FID. Mother Tongue: The Tadka Phonation Technique for speaking an
African Tonal Language – Krobo/Dangme/Ga of South-East Ghana. Watford 2001, UK. ISBN 0-9515442-4-1. [ Produced to facilitate tribal health education in the Mother Tongue] 165. Konotey-Ahulu FID. The supra-scientific in clinical medicine: a challenge for Professor
Know-All. Brit Med J 2001; 323(7327): 1452-1453 (22-29 Dec). View publication here --
> doi:10.1136/bmj.323.7327.1452
PMID:11751350 [PubMed-indexed for MEDLINE] 166. Konotey-Ahulu FID. AIDS in Africa. Lancet 2002; 360 (9343): 1424. Nov. 2 2002.
(Commenting on Paul Weidle & Colleagues paper ‘HIV/AIDS treatment and HIV vaccines
for Africa. Lancet 2002; 359: 2261-67': I mentioned cool reception of vaccine prospects
"Look here, for a vaccine to be worth its name, it must produce antibodies. Would you surrender your sero-negative status for a sero-positive one?") PMID: 12424013 [PubMed-indexed for MEDLINE] 168. Konotey-Ahulu FID. Wake up call and need for paradigm shift. Brit Med Journal 2003
‘Rapid E-Response' to Didier Fassin and Helen Schneider's article opened up for Education
and Debate: - The politics of AIDS in South Africa: beyond the controversies. Brit Med J
2003; 326; 495-497 (1 March 2003). View article here [7000 words with 70 references] 174a. Konotey-Ahulu FID. Aggrey of Africa. New African Aug/Sept
2004, page 4. "I was very surprised to find my name among the the ‘100 Greatest Africans
of all time'. I was even more surprised that Aggrey of Africa was not mentioned at all, which made me agree totally with your comment (NA, August/Sept) that in certain respects ‘the results are disappointing'. I would like to make two pleas. First, that my name be replaced by that of Dr James E K Aggrey, and secondly, that you allow me to write an article for a subsequent issue of New African which could not only help your readers worldwide realise why that great man was called ‘Aggrey of Africa', but also make those who voted for me forgive my suggestion that I be replaced by somebody else. Professor Felix Konotey-Ahulu, London, UK". [Editor's note: See Aggrey's on p 50 of this issue] See Reference 174b. 174b Konotey-Ahulu FID. Aggrey of Africa: "Only the best is good enough for Africa". New
October 2004 pp 50-51. [ Brief account of Dr James E Kwegyir Aggrey 1875-1927,
the Ghanaian visionary] "My people of Africa, we were createdin the image of God, but men have made us think that we are chickens, ad we still think we are, but we are eagles. Stretch forth your wings and fly! Don't be content with the food of chickens" Dr J E Kwegyir Aggrey. [Editor: This tribute for Black History Month was written by Prof Felix I D Konotey-Ahulu, the Dr Kwegyir Aggrey Distinguished Professor of Human Genetics at the University of Cape Coast, Ghana]. Access article at'Only+the+best+is+good+enough+for+Africa'.(BLACK+HI STORY.-a0124444704 175. Konotey-Ahulu FID. There is nothing mysterious about Kwashiorkor. BMJ 14 May
2005 Rapid Response
176. Konotey-Ahulu FID. Sickle-cell disease and the patient. Lancet 2005; 365(9457):
382-83 January 29-February 4. [Commenting on Marie Stuart & Ronald Nagel's "Sickle-cell disease" Seminar in Lancet 364: 1343-60, and Michaela Buckner's "Sickle-cell disease: from Sierra Leone to southeast London" Lancet 364: 1361, it is pointed out that "Stuart and Nagel missed something out of their Seminar, which Michaela emphasizes – circumstances."] PMID: 15680445 [PubMed-indexed for MEDLINE] 177. Konotey-Ahulu FID. Controlling the three "P"s in Africa. Lancet Aug 20-26 2005;
366(9486): 364. ["Developed countries successfully control what I call the three ‘P's
Politics, Poverty, and Population'. In developing countries, these get so out of hand that national health suffers. The more out of control the three ‘P's are, the less healthy the nation is. What we really need is a paradigm shift in our approach to all Africa's health problems, acknowledging also that the stellar qualities of our doctors make them a valuable export, especially to the USA". PMD: 16112297 [PubMed-indexed for MEDLINE] 188. Konotey-Ahulu FID. Historicity of The Lord Jesus Christ. (Christmas Message)
Ghanaian Times December 17 2005, page 6.
198. Konotey-Ahulu FID. Payment for Health Care (1) Ghanaian Times March 11 2006,
213. Konotey-Ahulu FID. Recovering lost knoweldge of traditional medicine by searching
historical herbal texts for potential new drugs. BMJ Rapid Response December 26 2006.

Konotey-Ahulu FID. Exposing Evolution's Icon. Creation 2006 Dec; 29(1): 16-19.
"Sickle cell has nothing to do with evolution".

Konotey-Ahulu FID. My stethoscope's bell and discovery of a new Parkinsonian
physical sign (Kap's sign) in clinical medicine. BMJ Rapid Response 6 February 2007

218. Konotey-Ahulu FID. The Remarkable African Ear: Phenomenon of Mid Pitch Arrest
Phenomenon in Krobo-Dangme-Gã Tonal Linguistics of South East Ghana. African American Museum of Philadelphia Award Lecture May 5 2007
220. Konotey-Ahulu FID. Dissemination of Research Results in Africa [Special Guest
Editorial] African Journal of Health Sciences 2007; 14: 1-2 January-June 2007
222. Konotey-Ahulu FID. Four bodyguards and the perils of unmasking scientific truths.
BMJ 2007; 335: 210-211. doi:10.1136/bmj.39268.553021.47 (July 28 2007) [To download and print out
223. Konotey-Ahulu FID. Who should best pharmacovigilate in developing countries? 14
September 2007 BMJ Rapid Response to Editorial

225. Konotey-Ahulu FID. Need for ethnic experts to tackle genetic public health. Lancet
2007; 370: 1836 doi:10.1016/50140-6736(07)61771-1

Konotey-Ahulu FID. Tonal languages, Genetics, Human Race and James Watson's
Clanger. (January 2008) clanger
230. Konotey-Ahulu FID. G6PD Deficiency in Ghanaians: How to recognise it.
http://blog.konotey-ahulu,com/blog/_archives/2008/1/16/3458557.html Jan. 16 2008
234. Konotey-Ahulu FID. The soul is suprascientific. BMJ Rapid Response 16 May 2008.

Konotey-Ahulu FID. The stethoscope is there for life and will remain for good. BMJ
Rapid Response May 28 2008.
236. Konotey-Ahulu FID. Poor care for sickle cell disease patients: This wake up call is
overdue BMJ Rapid Response May 28 2008 BMJ 2008; 336: 1152 to Susan Mayor "Enquiry shows poor care for patients with sickle cell disease" on National Confidential Enquiry into Patient Outcome and Death (NCEPOD) REPORT "SICKLE: A Sickle Crisis? (2008) [email protected]
238. Konotey-Ahulu FID. Social pathology of Cleft Palate in The African: Mathematical
Precision of Pitch Gaps in Tribal Tonal Linguistics. Ghana Medical Journal 2008; 42: 89-91. (June 2008). PMID: 19180210 [PubMed – indexed for MEDLINE] 20Cleft%20Palate.pdf Also seen on (vowel coloration
omitted on this NIH site).
240. Konotey-Ahulu FID. Current "hit and miss" care provision for sickle cell disease
patients in the UK. BMJ Rapid Response 22 July 2008

241. Konotey-Ahulu FID. MDG's Countdown to 2015, and "concern" for Africa. Lancet
2008; 372: 369-370. (Aug 2 2008) PMID:18675678 [PubMed-indexed for MEDLINE] DOI:

Konotey-Ahulu FID. Management of sickle cell disease versus management of the
sickle cell disease patient. BMJ Rapid Response 17 September 2008
244. Konotey-Ahulu FI D. Malaria and sickle cell: "Protection?" Or "No Protection?" –
Confusion reigns. BMJ Rapid Response October 13 2008.
251. Konotey-Ahulu FID. Fighting Malaria: Isn't the best approach through Environmental
Hygiene and Public Health? BMJ Rapid Response April 26 2009
Konotey-Ahulu FID. Combating malaria: Try public health measures in Africa too.
BMJ 2009; 338:b 1971 doi:10.1136/bmj.b1971 (May 20) PMID: 19457959 [PubMed - indexed for MEDLINE]
Konotey-Ahulu FID. Human Genetics Commission (HGC) and direct to consumer
Genetic Tests, leading to Genetic Counselling. BMJ Rapid Response May 27 2009 256. Konotey-Ahulu FID. In History of Dialysis in the UK: c. 1950 – 1980. Transcript of a
Witness Seminar Held By The Wellcome Trust Centre For The History of Medicine At UCL, London, On 26 February 2008. Edited by SM Crowther, LA Reynolds, and EM Tansey, Volume 37 of Wellcome Witnesses to Twentieth Century Medicine [ISBN 978 085484 122 6]], pages 49-51.
Konotey-Ahulu FID. Abdominal aortic aneurysm screening for men: Please
acknowledge a genetic dimension. BMJ 10 July 2009.

261. Konotey-Ahulu FID. Free health care for world's poorest countries without pre-
conditions? BMJ Rapid response Aug 7
http://www.bmj.comcgi/eletters/339/aug05_1/b3177#218219 [In response to Zosia Kmietowicz BMJ 2009;339.b3177 YET TO BE PUBLISHED
(2) Global Genome Sequencing: Some Ethical Considerations. In Howard University
National Human Genome Center Post-Inaugural Symposium on "1000 Genomes Project: On the Frontier of Personalised Medicine" at Ralph J Bunch International Affairs Center, Howard University, 2218 Sixth Street, NW Washington, District of Columbia, USA January (3) African Anthropogenetics and its contribution to World Medicine [Basic Medical
Sciences Award Lecture given at Third World Academy of Sciences (TWAS) Prize Giving
Ceremony in Dakar, Senegal on 21st November 1999]
(4) The New Genetics and how it affects you in Ghana [Inaugural Lecture April 2000, as
Dr Kwegyir Aggrey Distinguished Professor, Faculty of Science, University of Cape Coast, Ghana] (5) How to give Genetic Counselling to Illiterates. Lecture at Royal Society of Medicine,
London W1, to Ethnic Health Group 6 December 2003. [Using ‘Ache/Ache' Diagram shown
on (6) Some aspects of the Macrogenetics of Hypertension in African People. Lecture at
Ethnic Health Symposium on Hypertension at the Royal Society of Medicine, London on 4 March 2004. [Elaborating and illustrating Jonathan Addy's observation that Ghanaian hypertension was inherited as homozygous Mendelian Recessive . ] (7) An entire African tribe with perfect mid pitch. [A new phenomenon illustrated in article
(8) AIDS IN AFRICA: Obstacles to Health Care Delivery. [Invited Lecture given at the 53rd
Meeting of the International Association of Physicians for the Oversease Services (IAPOS)
in London on 14th May 1999, and at an Internationa; Conference in Cape Town November 2002 on ‘Sustainable Health Care Delivery for the New Millennium']
(9) Konotey-Ahulu FID. How To Avoid Losing Our Mother Tongue. Substance of Lecture
given atthe British Council Accra November 2007
(10) Konotey-Ahulu FID. Clinical Genetics: British Contributions Overseas: Witness of an


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