"P" - No Medical Care:

Elevated psychological stress predicts reduced estradiol concentrations in young women

University of Portland Elevated psychological stress predicts reduced estradiol concentrations in young womenJames R. Roney Zachary L. SimmonsUniversity of Portland, simmonsz@up.edu Follow this and additional works at: Citation: Pilot Scholars Version (Modified MLA Style)Roney, James R. and Simmons, Zachary L., "Elevated psychological stress predicts reduced estradiol concentrations in young women"(2014). Psychological Sciences Faculty Publications and Presentations. Paper 8.


The pharmaceutical industry in Brazil Market overview and trends Overview of the for labor began to stabilize in 2013 and started to lose some of its vigor and there is a feeling among specialists that the market will tend towards a rise in unemployment. Therefore, some reduction in salary levels can be expected in the local

Microsoft word - psr_vol.15_b_09_third-person effects in the stock market perception.doc

Jae-Min Jung and Ho-Yeon Kim: Third-person Effects in the Stock Market:Perception of Experts & Non-experts and Impacts on Attitude Third-person Effects in the Stock Market: Perception of Experts & Non-experts and Impacts on Attitude Jae-Min Jung* and Ho-Yeon Kim** Abstract: The third-person effect was tested by examining whether people perceive a greater influence of unidentified information recommending stocks in the Internet on others than on themselves. Findings confirm the third-person effect but also show subjects with stock market experience perceive a greater influence on others than did subjects with no stock market experience. Additionally, subjects demonstrated a larger third-person effect when "others" are specified as novice investors who have little knowledge or experience in stock trading than when "others" are identified as experienced traders. After controlling for SES and interest and experience in stock trading, the third-person perception remained. Keywords: Third-person perception, Behavioral effect, Stock market, Internet information, Expert

Microsoft word - sandoz_final_word_text[1]

A MINI REVIEW Viridis BioPharma Pvt. Ltd. Viridis BioPharma Pvt. Ltd. "VITAMIN K2-7" A MINI REVIEW Had this review been written just 25 years ago, the metabolism of vitamin K would have been considered just in the context of its role in haemostasis. During the last 25 years there has been intensive research with the vitamin K and its analogues which has surfaced the role of vitamin K2-7 (natural) and K2-4 (synthetic) in the human physiology in multiple functions. The newly discovered functions extend throughout the body in the Ca metabolism giving rise to the label "Calcium Paradox" because Ca gets deposited in the vasculature instead of the required target bones. Vitamin K is an essential fat-soluble micronutrient which is needed for a unique posttranslational chemical modification in a small group of proteins with calcium-binding properties, collectively known as vitamin K – dependent proteins (VKD proteins) or Gla-proteins. This review is general as well as specific to K2-7 to bring out its importance amongst other vitamin K analogues. INTRODUCTION


MINIMALLY INVASIVE ANTRAL MEMBRANE BALLOON ELEVATION • MAZOR ET AL Flapless Approach to Maxillary Sinus Augmentation Using Minimally Invasive Antral Membrane Balloon Elevation Ziv Mazor, DMD,* Efraim Kfir, DMD,† Adi Lorean, DMD,‡ Eitan Mijiritsky, DMD,§ and Robert A. Horowitz, DDS储 Posteriormaxillaryimplantplace- In the atrophic posterior max- floor. The surgical procedure was

For the use of registered medical practitioner or a hospital or a laboratory only

For the use of Registered Medical Practitioner or a Hospital or a Laboratory only OD-PEPTM Fixed Dose Combination of Pantoprazole and Domperidone DESCRIPTION OD-PEPTM (a Fixed dose combination of Pantoprazole and Domperidone) contains Pantoprazole which is chemically sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sesquihydrate and Domperidone which is chemically 5-chloro-1-[1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]-piperidin-4 -yl]-1,3-dihydro-2H-benzimidazol-2-one. OD-PEPTM capsule is Transparent/Transparent size "1" hard gelatin capsule filled with one yellow colored, round, beveled, biconvex, enteric coated tablet of Pantoprazole and one each of white/ red colored, round, beveled, biconvex, film coated tablet of immediate-release/ delayed-release tablet of Domperidone.

Lwwus_aia_200329 117.133

Multimodal Systemic and Adam Young, MDAsokumar Buvanendran, MDRush University Medical CenterChicago, Illinois Ambulatory surgery encompasses the majority of surgical proce- dures performed in the United States. The number of proceduresperformed on an ambulatory basis has increased owing to improve-ments in surgical technology, anesthetic techniques, and pharmacol-ogy—specifically analgesic agents. The latter is important as there is anincreasing trend of performing more painful procedures on anoutpatient Inadequate management of pain or side effects frommedications (such as opioids) can lead to decreased patient satisfactionand delayed discharge. Multimodal analgesia captures the effectivenessof individual agents in optimal dosages that maximize efficacy andminimize side effects. This important concept includes the theory thatagents with different mechanisms of may have synergisticeffects in preventing or treating pain. Joshi offered guidelines onconstructing a multimodal analgesia strategy that, in addition to regionalor local anesthesia, included scheduled administration of nonopioidanalgesics [eg, acetaminophen, nonsteroidal anti-inflammatory drugs(NSAIDs), or cyclooxygenase (COX)-2 inhibitors] using oral opioids onlyfor breakthrough pain.Successful regimens for outpatient (andinpatient) procedures have since been proposed that follow theseprinciples.These regimens must be tailored to individual patients,keeping in mind the procedure being performed, side effects ofindividual medications, and patients' preexisting medical conditions.

Head lice: evidence-based guidelines based on the stafford report

HEAD LICE: EVIDENCE-BASED GUIDELINES BASED ON THE STAFFORD REPORT 2012 UPDATE Produced by Public Health Medicine Environmental Background and Acknowledgements 1.1. The Original 1998 Stafford Report , 2002 and 2012 Updates There is a need for a consistent, integrated, rational approach to the prevention and control of head louse infection in the UK. Myths and misinformation abound and there has been insufficient high quality scientific research for the production of authoritative, evidence-based policies. The national professional organisation for Consultants in Communicable Disease Control (CCDC) in Great Britain and Ireland is the Public Health Medicine Environmental Group (PHMEG). In 1997 the PHMEG commissioned three members to produce guidance on head louse control. These members reviewed the available evidence, discussed the issues with a multiprofessional working group and consulted widely amongst colleagues around the country to gain as balanced a view as possible on what might constitute a rational base for a national approach to the problem. Supported by the Deputy Director of the Cambridge Medical Entomology Centre, the three members produced a document that became known as the "Stafford Report" 1, since the authors met in Stafford. Referencing was deliberately omitted, since it was intended to be a "best practice" guidance document and there was insufficient evidence of high quality to produce a comprehensive authoritative scientific statement. The Stafford Report was distributed for wide consultation and in its final version was formally accepted by the PHMEG in June 1998. Since then, modified according to local needs, it has been widely adopted and has been found to be a rational and logical approach for devising local policies and providing useful informational materials for professionals and public alike. This was complemented by a video produced by PHMEG. The 1998 Stafford Report1 was written by the "Stafford Group": Dr Robert Aston CCDC, Bolton Health Authority Dr Harsh Duggal, CCDC, South Staffordshire Health Authority Dr John Simpson, CCDC, West Surrey Health Authority Advised by:


Primary prevention of breast cancer: state of the art in 2012 Fabienne Liebensa*, Birgit Carlya, Pino Cusumanob, Virginie Lienarta, Serge Rozenberga a ISALA Breast Unit and Prevention Center, OBGYN department, CHU Saint Pierre, Brussels, ULB-VUB. bBreast Unit, CHC Saint Joseph and CHU Sart Tilman, Liège, ULg *Corresponding author: Fabienne Liebens MD, ISALA Breast Unit and Prevention Center, CHU Saint Pierre, 290 rue Haute, 1000 Bruxelles.

Po 3228 cover

VOLUME 4 • NUMBER 1 • JANUARY 2005 Cosmetic Dermatology Edited by Zoe Diana Draelos Reprinted Article: Idebenone: a new antioxidant – Part I. Relative assessment of oxidativestress protection capacity compared to commonly known antioxidants D H McDaniel, B A Neudecker, J C DiNardo, J A Lewis, II & H I Maibach


Revista Estado y Políticas Públicas Nº 3. Año 2014. ISSN 2310-550X pp 79-89 Bruno Fornillo "¿A qué llamamos Recursos Naturales Estratégicos?." ¿A qué llamamos Recursos Naturales Estratégicos? El caso de las baterías de litio en Argentina What Do We Mean by "Natural Strategic Resources"? The Case of Lithium Batteries in Argentina


Nek4 Regulates Entry into ReplicativeSenescence and the Response to DNA Damage in Human Fibroblasts Christine L. Nguyen, Richard Possemato, Erica L. Bauerlein, Anyong Xie, Ralph Scully and William C. HahnMol. Cell. Biol. 2012, 32(19):3963. DOI:10.1128/MCB.00436-12. Published Ahead of Print 30 July 2012.


Novel Use of Erbium:YAG (2,940-nm) Laser for FractionalAblative Photothermolysis in the Treatment of PhotodamagedFacial Skin: A Pilot Study MOSHE LAPIDOTH, MD, MPH,y MARINA EMIKO YAGIMA ODO, MD,z AND LILIAN MAYUMI ODO, MDz The use of CO2 or conventional erbium laser ablation or more recent nonablative laser photothermolysis for skin rejuvenation is associated with significant disadvantages.


The Primordial Psyche Abstract: Scientific materialism is still influential in certain academicspheres. In this article, I examine multiple lines of empirical evidenceshowing that this ideology, while partially true, is woefully incompleteand, therefore, obsolete. This evidence indicates that we humans can-not be reduced to powerless, biophysical machines since the psychegreatly influences the activity of the brain and the body, and can oper-ate telosomatically. Based on this evidence, I introduce the Theory ofPsychelementarity (TOP) and present a few predictions. This theoryproposes that the psyche plays a role as primordial as that of matter,energy, and space-time. Another central premise of this theory is thatthe psyche cannot be reduced to physical processes. The TOPaccounts for a number of well-studied psychophysical phenomena,which are reinterpreted in light of a post-materialist perspective. Thistheory also accounts for anomalous phenomena that are currentlyrejected by materialists.


Proceeding of 6th ICGRC 2015 6-Gingerol from Zingiberaceae as a Result of Reverse Docking for Prostate's Cancer Potential Drug Candidate Haqqi Anajili Setyanto1, Arindra Trisna Widiansyah1, Zainul Mustofa1 1 Postgraduate of Educational Biology, State University of Malang, Malang, Indonesia Prostate cancer is a cancer that attacks the prostate gland causing the death rate which is high enough. One of the causes ofprostate cancer is the androgen receptor (AR) in the gland cells that initiates the formation of excess cell proliferation, thuscausing prostate cancer. AR inhibitor that is known is antiandrogen (biculatamide and enzalutamide). This study aimed to test the6-gingerol compound of ginger as an AR inhibitor drug candidate for prostate cancer using silico methode. The 3D structure ofthe 6-gingerol compound was taken from PubChem, the prediction of targeted protein used SwissTargetPrediction andPharmapper, analysis and docking 6-gingerol and antiandrogens with AR using Pyrx software, visualization compounds andprotein interactions using PyMOLsoftware. Visualization results shows that the interaction of 6-gingerol, biculatamide, andenzalutamide with AR have the same site. This proves that the 6-gingerol is potential as anAR inhibitor candidate.

Statin alternatives or just placebo

Chin Med J 2008;121(16):1588-1594 Review article Statin alternatives or just placebo: an objective review of omega-3, red yeast rice and garlic in cardiovascular therapeutics Hean Teik Ong and Jin Seng Cheah Keywords: statin; omega-3, red yeast rice; garlic; cardiovascular therapeutics Objective The aim of this review is to objectively access the trial evidence on the role of omega-3, red yeast rice and garlic in preventing clinical cardiovascular events. Given the large number of clinical trials favoring statin use in cardiovascular disease, it is important to see if evidence is available for these supplements and whether they could replace statin therapy. Data source A PubMed search was conducted using the keywords ‘trial, omega-3, red yeast rice, xuezhikang, garlic, cholesterol, cardiovascular, outcomes'; the resulting trials were reviewed together with the references quoted in the papers obtained. Study selection The studies selected are prospective, randomized, placebo-controlled studies with predefined clinical cardiovascular end-points recruiting at least 2000 patients, with a follow-up over 2 years. Results Modest dose omega-3 fatty acid has been shown in GISSI-P (11 324 patients, follow-up 3.5 years) to produce a reduction in sudden death of 45%, and in cardiac death of 35%, acting probably via an anti-arrhythmic effect. In JELIS (18 645 patients, follow-up 4.6 years), high dose omega-3 given to Japanese patients on a high fish diet and already on statin treatment produced further benefit with a 19% reduction of nonfatal cardiovascular outcomes; fatal cardiac events are not affected. CCSPS (4870 patients, follow-up 4 years), a secondary prevention trial using xuezhikang, a commercial red yeast rice preparation, produced a 46% reduction in nonfatal myocardial infarction and coronary death. There has been no trial to show that garlic reduces clinical cardiovascular outcomes. A rigorous trial with constant assessment of chemicals in the study material in 192 patients found that over a 6-month follow-up, raw garlic and 2 commercial preparations do not significantly affect lipid levels. Conclusions Omega-3 in modest doses reduces cardiac deaths, and in high doses reduces nonfatal cardiovascular events. Red yeast rice reduces adverse cardiac events to a similar degree as the statins. It is unlikely that garlic is useful in preventing cardiovascular disease.

Apc family camp application

2015 ALBERTA PIONEER FAMILY CAMP APPLICATION info@pioneercamps.ab.ca FAMILY CAMP REGISTER BEFORE January 16th July 31st - August 3rd and get $50 off per family! A camp for the whole family! We can accommodate up to 8 family members per cabin. Participate in activities together as a family.

Fall bulletin.for real

A Clinical Plan for MDMA (Ecstasy) in the Treatment of Post-Traumatic Stress Disorder (PTSD): Partnering with the FDA Rick Doblin, Ph.D. The following article was originally published in the April-June 2002 special MDMA issue of theJournal of Psychoactive Drugs (www.hafci.org). The article presents the rationale behind MAPS'efforts to sponsor research in Spain, the US and Israel investigating MDMA's potential in treatingpatients suffering from posttraumatic stress disorder (PTSD). This document is the clearest expres-sion to date of MAPS' role as a membership-based non-profit pharmaceutical company, as distinctfrom MAPS' other research and educational functions. We are reprinting this article in order toexplain in detail to MAPS' membership the vision and strategy animating MAPS' MDMA/PTSD researchprojects and associated fundraising efforts. A mission statement in a way, this article should help toexplain why MAPS has chosen the ambitious goal of developing MDMA into an FDA-approved prescrip-tion medicine in the treatment of PTSD. Since this article was written, the Spain MDMA/PTSD re-search project has been halted (hopefully temporarily) due to political pressure, and it has takenlonger than expected to obtain DEA and IRB permission to start the US MDMA/PTSD project.

Pc131086 1.20

This article is a Plant Cell Advance Online Publication. The date of its first appearance online is the official date of publication. The article has beenedited and the authors have corrected proofs, but minor changes could be made before the final version is published. Posting this version onlinereduces the time to publication by several weeks. A Secreted Effector Protein of Ustilago maydis Guides MaizeLeaf Cells to Form Tumors

A21045 schizophrenia doc 2

A21045 schizophrenia doc 2 28/5/04 12:46 pm Page 1 Support and Guidance forEveryone Affected by Schizophrenia A21045 schizophrenia doc 2 28/5/04 12:46 pm Page 2 Inside front cover Copyright © Bristol-Myers Squibb Company and Otsuka Pharmaceutical Co., Ltd. 2004 All rights reserved, including the right of reproduction in whole or in part in any form.

(microsoft word - ciencia_ y_tecnolog 355a_el_riesgo_del_abandono.doc)

Ciencia y Tecnología: el riesgo del abandono Jorge Labarreda González. Algo que todo mundo sabe es que no hay mejor medicina para combatir las enfermedades que la prevención. De manera lógica se deduce: la fortaleza de una sociedad depende en gran parte de las medidas que tome para hacer frente a la contingencia, entendida esta, como todo aquello que se encuentra latente, con la

56105 the psbt bcbook div 2 23-mar-11 with jc cover.pages

Great-West Life is a leading Canadian life and health insurer. Great-West Life's financial security advisors work with our clients from coast to coast to help them secure their financial future. We provide a wide range of retirement savings and income plans; as well as life, disability and critical illness insurance for individuals and families. As a leading provider of employee benefits in


Point of Care Diagnostics DIPSCAN 10 PLUS with extra opiates (AMP, BUP, BZD, COC, MET, MTD, OPI, OXY, TRA, THC) Multi Drug Screen teSt INTENDED USE Dipscan 10 Plus is an immunochromatography based one step in vitro The appearance of a line next to the Control "C" and the absence of a line

Vol 5(1)

FREQUENCY OF DEPRESSIVE AND ANXIETY SYMPTOMS AMONG PATIENTS ON INTER- FERON AND PEGYLATED INTERFERON Muhammad Waseem Shaikh1, Farah Ahmad2*, Gulnaz Shaikh1, Syed Hasan Danish2, Kirpal Das Makheja3, Minhaj A Qidwai4 1Liaquat University Hospital Jamshoro, 2Department of Community Health Sciences , Ziauddin University

Metformin for the treatment of the polycystic ovary syndrome

clinical therapeutics Metformin for the Treatment of the Polycystic Ovary Syndrome John E. Nestler, M.D. This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines,


Informed Consent: Valtrex (valacyclovir) or Famvir (famciclovir) Treatment for Chronic Fatigue Syndrome From Richard Podell, M.D., MPH, August 3, 2014 Background: Currently there are no proven effective treatments for chronic fatigue Most experts strongly suspect that Herpes Class viruses such as Epstein Barr Virus (EBV), HHV-6, and/or Cytomegalovirus (CMV) play an important role for some but not all CFS patients.


The Pharmaceutical Industry 6.1. Industry Argentina's pharmaceutical industry includes 150 laboratories, and represents a very dynamic and competitive industry. Argentine pharmaceutical companies dominate 70% of the market. Top players include Laboratorios Roemmers and Laboratorios Bagó Pharmaceuticals are available in various presentations in Argentina, such as solids, semi-solids, injectables, liquids, etc. During 2007's first two quarters, the pharmaceutical industry grew 18.5% from 2006. Further, internal demand increased 16.1%, and exports increased 39.5% during 2007. The industry's sales figures continued expanding throughout 2007. During the fourth quarter of 2007, pharmaceuticals in major demand included those for digestive problems (USD $103 million – 17.3% of the total market), followed by nervous system products (USD $102 million – 17.2% of the total market), infection treatment (USD $76 million – 12.8% of the total market) and cardiovascular treatments (USD $74 million –12.3% of the total market). These four groups encompass 59.6% of pharmaceutical sales in Argentina.

Meta: characterization of medical treatments at different abstraction levels

Politecnico di Torino Porto Institutional Repository [Article] MeTA: Characterization of medical treatments at different abstractionlevels Original Citation:Dario Antonelli; Elena Baralis; Giulia Bruno; Luca Cagliero; Tania Cerquitelli; Silvia Chiusano;Paolo Garza; Naeem A. Mahoto (2015). MeTA: Characterization of medical treatments at differentabstraction levels. In: vol. 6 n. 4, pp. 1-25. - ISSN 2157-6904


A Natural Approach to Menopause Every day, in hundreds of doctors' offices, the same Study (HERS) confirmed that hormones did not reduce the conversation takes place between women going through risk of heart problems in postmenopausal women with heart menopause and their doctors. The doctor writes out disease. In fact, their risk of blood clots doubled and their need

Kompendium progesteron

Natürliches mikronisiertes Indikationen und Dosierungen Übersicht über die empfohlenen Dosierungen von Hormonsubstitution während und nach der Menopause Drohender Abort / Prävention habitueller Aborte Prävention einer Frühgeburt und drohende Frühgeburt (vorzeitige Wehen) Unterstützung der Lutealphase bei stimulierten IVF-Zyklen nach Agonisten- oder Antagonisteneinsatz


Int J Ment Health AddictionDOI 10.1007/s11469-014-9496-z Guideline for Screening, Diagnosis and Treatmentof ADHD in Adults with Substance Use Disorders Frieda Matthys & Steven Stes & Wim van den Brink &Peter Joostens & David Möbius & Sabine Tremmery &Bernard Sabbe # Springer Science+Business Media New York 2014 Abstract Currently there is no guideline for the screening, diagnosis and treatment of adultattention deficit/hyperactivity disorder (ADHD) in patients with a substance use disorder(SUD). The aim was to develop such a guideline, starting out from a systematic review andbased on the methodology of the Scottish Intercollegiate Guideline Network (SIGN). Due tothe lack of scientific evidence on some of the topics, the guideline is a combination of evidencebased and practice based recommendations. Given the high prevalence of ADHD in treatmentseeking SUD patients and the availability of valid screening instruments, all treatment seekingSUD patients should be screened for ADHD. Diagnosis of ADHD should be based on clinicalobservation and history taking, including informant data. Integrated treatment of ADHD andSUD is recommended, including pharmacotherapy, psycho-education, coaching, and cognitive

Methadone-drug interactions

(*Medications, illicit drugs, & other substances) Stewart B. Leavitt, MA, PhD; Executive Director, Pain Treatment Topics; January 2006 Reviewed but not revised June 2010 Medical Reviewers: James D. Toombs, MD; Lee Kral, PharmD, BCPS Prior Publication History 3rd Edition: November 2005 Revision/Update, Addiction Treatment Forum Special Report, ATForum.com.

Microsoft word - description_project_pipelinenew2.doc

 The PVEout project within the European 5th framework, NRU T. Dyrby, 06-07-03 The pipeline program for PVElab PARTIAL VOLUME ERROR .3 THE PIPELINE PROGRAM .4 THE USER-INTERFACE .4 Restrictions using project .7 Syntax and indices.8 The project field .9 The pipeline field and sub-fields .10 The taskDone field and its sub-fields .12

Jimd4221 681.693

J. Inherit. Metab. Dis. 25 (2002) 681 693# SSIEM and Kluwer Academic Publishers. Printed in the Netherlands. The osteodystrophy of mucolipidosis type IIIand the effects of intravenous pamidronatetreatment OBINSON , N. BAKER , J. NOBLE , A. KING , G. DAVID , ILLENCE , P. HOFMAN and T. CUNDY * 1Department of Paediatrics, Nelson Hospital, Nelson; 2Department of Pathology,Middlemore Hospital, Auckland, New Zealand; 3Academic Department of MedicalGenetics, The Children's Hospital, Westmead, Australia; 4Faculty of Medicine &Health Sciences, University of Auckland, Auckland, New Zealand


Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults : Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache S. Holland, S.D. Silberstein, F. Freitag, et al. April 24, 2012 This information is current as of

Prostate cancer guidelines forum: 5/6 february 2005

Prostate Cancer Diagnostic and Treatment Guidelines The Prostate Cancer Foundation of South Africa Publication Date: June 2013 ORIGINAL AUTHORS Prof. A M. Segone, Prof. M. Haffejee, Prof. S. Wentzel, Prof. C. F. Heyns, Prof. S. B. A. Mutambirwa, Dr. L. Coetzee, Prof. R. Barnes, D.r P. Porteous, Dr. M. Mackenzie, Dr. M.


ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Feb. 2011, p. 637–648 Copyright © 2011, American Society for Microbiology. All Rights Reserved. A Rapid, High-Throughput Viability Assay for Blastocystis spp. Reveals Metronidazole Resistance and Extensive Subtype-Dependent Variations in Drug Susceptibilities䌤 Haris Mirza,1 Joshua D. W. Teo,1 Jacqui Upcroft,2 and Kevin S. W. Tan1*

Victory over cancer – part one: making the unthinkable possible

Facts No One Can Ignore Any Longer Victory Over Cancer – Part One: Making the Unthinkable Possible Chapter I − Facts No One Can Ignore Any Longer The Sobering Cancer Death Statistics Cancer Is the Third Largest Cause of Death in of the World Health Organization (WHO) The Industrialised World • At the beginning of the 21st Century, the cancer epidemic


SPA Pain Meeting syllabus 2014 Developmental Pharmacokinetics/Pharmacodynamics of Parenteral Opiates and NSAIDS in Infants: What are the Problems? The development of microassay techniques for drug concentrations in the late 1970s and 1980s allowed investigations of the metabolism of drugs in pediatric populations. The study of pharmacokinetics (drug distribution and handling in the body-PK) in children and infants and of pharmacodynamics (the effects of drugs on the body – PD) grew as small blood/serum samples could be analyzed for drug concentrations. Computer-assisted analysis of concentration vs. time graphs facilitated computation of pharmacokinetic parameters, such as clearance, volume of distribution and elimination half-life. This information showed differences between adult drug handling and that found in children and infants, helping to explain the different effects or durations of effect seen. Applying these analyses to opiate analgesics involved many investigators including this speaker. Pharmacodynamic effects may be more complex since this involves not only pharmacokinetic factors, but factors such as access to sites of action, different receptor avidity or number which may differ in different ages, races, ethnicities or with different genetic variants linked to opiate action.

Microsoft word - annex 1.doc

PUSH DRAFT ECONOMIC DEVELOPMENT STRATEGY CONSULTATION Start: 21st July 2010 End: 21st September 2010 Table of Contents Foreward ………………………………….….3 Executive Summary.5 Questions.7 Your Views.8 How to Respond.9 Next Steps.9 Annex A – List of consultees.9 Foreword This Economic Development Strategy sets out our ambitions for the PUSH area in the light of substantial changes to the economic and policy environment since we developed our previous strategy. Our fundamental ambitions have not changed. We wish to see a more prosperous future for the residents of South Hampshire. We wish to see everyone sharing in the benefits, with reduced levels of deprivation and increased levels of labour market participation. We wish to see our cities fulfil their potential as engines of economic growth and we wish to see the sub-region becoming an even greater place to live, work and do business, offering a fantastic quality of life. In order to deliver this, our strategy is centred on sustainable development, on ensuring the quality of life which we value so highly is enhanced and enriched, not jeopardised. However, the context has changed. The recession has led to more of our residents becoming unemployed. It has created substantial challenges for both public and private sector investment both now and in the future. The change in Westminster government has changed the public policy environment. Whilst these changes could be seen as challenges, we see them as opportunities. They have forced us to look at how we work in this sub-region and how we can do things more efficiently. We must work together, pool our resources and align our priorities around a common agenda. We already have a track record of doing this in this sub-region. We are not starting from scratch, we are already ahead of the game. We therefore believe we can deliver higher levels of growth, we can deliver more and better for less, we can grasp the opportunities afforded to us through the changes being proposed by the Coalition. Central to our strategy is taking action to be innovative in how we deliver and fund activities. Central to our strategy is joining up the public and private sectors to work together. Central to our strategy is using the assets we already have in the sub-region; our people, our world class businesses; our universities and our fantastic natural environment. We have identified the areas of our economy where we need to invest and focus our efforts. Those sectors where we have great specialisms, world class innovation and skills and opportunities to drive economic output, those sectors which will underpin employment growth and create opportunities for our residents to access jobs and those sectors which are fundamental to South Hampshire offering a high quality of life.


INSERM.book Page 237 Friday, September 2, 2005 2:56 PM Les investigations biologiques dans le domaine de l'agressivité et de la vio-lence sont relativement récentes et ont d'abord porté sur des paramètrespériphériques, comme par exemple des caractéristiques particulières durythme cardiaque ou encore les taux sanguins de certaines hormones oumétabolites. En dépit de leur caractère systématique et a priori non (ou peu)ciblé, ces recherches ont permis de mettre en évidence des particularitésbiologiques qui ont pu secondairement être mises en relation avec d'autresparticularités, neurobiologiques cette fois, concernant certains neurotrans-metteurs dans le système nerveux central. C'est ainsi, par exemple, quel'accroissement des manifestations agressives (impulsives) chez certainssujets suite à une diminution de l'apport alimentaire en tryptophane (acideaminé essentiel, non synthétisé par l'organisme) a pu être relié à un ralentis-sement d'activité des neurones sérotoninergiques (qui utilisent la sérotonine– 5-HT – comme neuromédiateur) cérébraux. En parallèle, le développe-ment de modèles animaux pertinents, en particulier chez les rongeurs (rat,hamster, souris, y compris des lignées génétiquement modifiées), mais aussichez les primates, a permis d'affiner les connaissances sur les neuromédia-teurs et neurohormones tels que les monoamines et certains neuropeptidesimpliqués dans le contrôle et l'expression de comportements impulsifs etagressifs et le passage à l'acte violent. De plus, les données issues de ces tra-vaux ont pu être croisées avec celles concernant les mécanismes d'actionneurobiologiques de psychotropes agissant sur ces comportements, en parti-culier les neuroleptiques, les antidépresseurs et les tranquilisants/anxiolyti-ques. Enfin, le développement récent des techniques de neuroimagerie laisseaugurer d'une nouvelle ère dans les recherches sur les mécanismesneurobiologiques qui sous-tendent les comportements impulsifs, agressifset violents, avec l'identification des circuits neuronaux concernés. D'ores etdéjà, les données obtenues dans ce cadre s'inscrivent dans une certainecohérence avec les observations antérieures chez des sujets cérébro-lésés etsuite à des lésions anatomiques précises chez l'animal. En particulier, lesunes et les autres pointent les structures limbiques (hippocampe, hypothala-mus, septum, amygdate, noyau de la strie terminale) et le cortex cingulaireantérieur et orbito-frontal comme étant les zones cérébrales qui présententdes modifications d'activité directement en relation avec des manifestations


AG Productions Ltd.11570 Dona Evita DriveStudio City, CA 91604(323) 822-1957 EXT. FACTORY RUINS - NIGHT Whiffs of fog drift across the darkness as the moon emerges from behind the clouds illuminating crumbling cement blocks and twisted steel overgrown by weeds. ARIA DE WINTER, dressed as a goth girl, climbs over the cement blocks carrying a bouquet of roses. She is in her mid forties, her face is care worn. The years have not been kind to her. She lays the roses on the ground and steps back.

Rz fb prokopp mai 14.indd

Zugestellt durch die Post.at. Angebote gültig bis 31.05.2014 Druckfehler, Änderungen und Verfügbarkeit vorbehalten. Mit 300 Bonuspunkten Mit 200 Bonuspunkten Mit 600 Bonuspunkten VOLLKRAFT DR. GRANDEL • Helle & knackig Carbobpulver ist im Fruchtige Brausetabletten mit erfrischendem aromatische Kerne


King Drug Decision May Be A Turning Point In Pay-For-Delay August 7, 2015 By Andrew S. Wellin Law360, New York (August 7, 2015, 2:07 PM ET) -- Recently, the Third Circuit issued the first federal appellate decision interpreting the landmark decision inv. Actavis Inc.[1], potentially greatly expanding the scope of liability for settling parties in reverse payment cases. The Third Circuit held in King Drug Co. of Florence Inc. v. Smithkline Beecham Corp. that a pioneer drug manufacturer's agreement not to market an authorized generic product during a generic challenger's 180-day exclusivity period to settle litigation under the Hatch-Waxman Act is subject to rule of reason scrutiny under the Sherman Act.[2] This is significant because post-Actavis the district courts have reached conflicting determinations as to whether noncash compensation, such as the "no-AG" deal in King Drug, constitutes an illegal reverse payment.[3] So-called "reverse payments" occur when a pioneer drug manufacturer pays the alleged generic infringer to drop its patent challenge and delay its market entry. King Drug is the first word from the federal appellate judiciary and thus may serve to greatly expand the scope of liability for settling parties if courts outside the Third Circuit follow its lead. The dispute in King Drug centers around


DOSE-RESPONSE OF PORCINE OVARIAN GRANULOSA CELLS TO AMYGDALIN TREATMENT COMBINED WITH DEOXYNIVALENOL Marek Halenár*, Marína Medveďová, Nora Maruniaková, Dagmara Packová, Adriana Kolesárová Address(es): Ing. Marek Haklenár, Department of Animal Physiology, Faculty of Biotechnology and Food Sciences, Slovak University of Agriculture in Nitra, Tr. A. Hlinku 2, 949 76 Nitra, Slovak Republic. *Corresponding author: halenarmarek@gmail.com


PHYSICAL REVIEW B 82, 184512 共2010兲 Enhancing the critical current in quasiperiodic pinning arrays below and above the matching magnetic flux V. R. Misko,1,2 D. Bothner,3 M. Kemmler,3 R. Kleiner,3 D. Koelle,3 F. M. Peeters,1 and Franco Nori2,4 1Departement Fysica, Universiteit Antwerpen, B-2020 Antwerpen, Belgium 2Advanced Science Institute, RIKEN, Wako-shi, Saitama 351-0198, Japan

High-resolution x-ray telescopes

High-resolution x-ray telescopes Stephen L. O‘Dell*a, Roger J. Brissendenb, William N. Davisb, Ronald F. Elsnera, Martin Elvisb, Mark Freemanb, Terry Gaetzb, Paul Gorensteinb, Mikhail V. Gubareva, Diab Jeriusb, Michael Judab, Jeffery J. Kolodziejczaka, Stephen S. Murrayb,c, Robert Petred, William Podgorskib, Brian D. Ramseya, Paul B. Reidb, Timo Sahad, Daniel A. Schwartzb, Susan Trolier-McKinstrye,

Microsoft word - priclinbical_14.7.1

Vol 2 Issue 2 Jul –Dec 2011 76-80. Print ISSN – 2229 7502 Bioavailability studies of Pioglitazone with Antacid – An Invivo Evaluation in Human Volunteers S.Thirumurugu1*, V.Parthasarathy1, D.C.Arumainayagam2, and 1Department of Pharmacy, Annamalai University, Annamalai nagar, Tamilnadu, 2Department of Medicine, Rajah Muthiah Medical College & Hospital, Annamalai University,


HEROIN ADDICTION & Pacini Editore & AU CNS Heroin Addict Relat Clin Probl 2011; 13(2): 5-40 Basics on Addiction: a training package for medical practitioners or psychiatrists who treat opioid dependenceIcro Maremmani 1, Matteo Pacini 2, Pier Paolo Pani 3, on behalf of the 'Basics on Addiction Group' 1 Vincent P. Dole Dual Diagnosis Unit, Santa Chiara University Hospital, Department of Psychiatry, NPB, University


Endocrinologie et psychiatrie Résumé. – La survenue de troubles mentaux au cours de pathologies endocriniennes est un fait établi depuisplus d'un siècle. Réciproquement, des traumatismes psychologiques peuvent avoir un rôle dans ledéclenchement de certaines endocrinopathies, comme dans la maladie de Basedow. Ces dernières années ontvu le développement des examens neuroendocrinologiques chez des patients psychiatriques indemnes detoute affection endocrinienne, afin d'évaluer l'activité du système limbo-hypothalamo-hypophysaire. Lesobjectifs de ces explorations sont de trois ordres : 1) diagnostique (mise en évidence d'« indicateurs » ou de« marqueurs » de trait ou d'état d'affection psychiatrique) ; 2) physiopathologique (à partir de l'évaluationde la réponse fonctionnelle des axes neuroendocriniens à des stimuli spécifiques) ; 3) thérapeutique(détermination de critères prédictifs de réponses à certaines classes de psychotropes ; suivi de l'évolution desmarqueurs d'état en fonction de l'évolution clinique dans une perspective pronostique ; modificationsinduites dans une perspective pharmacologique).Cet article se propose de synthétiser l'état actuel des connaissances utiles pour le clinicien en adoptant, dansla mesure du possible, pour chaque axe hormonal envisagé (thyréotrope, corticotrope, mammotrope,gonadotrope, somatotrope – ainsi que pour les autres hormones [de la posthypophyse, de l'épiphyse, desparathyroïdes]) une organisation commune : physiologie ; troubles mentaux au cours d'endocrinopathies ;études chez les patients psychiatriques : principaux dosages statiques (en situation basale et au cours dunycthémère), tests dynamiques (freination, stimulation), hypothèses physiopathologiques, évolution deshormones au cours de thérapeutiques psychotropes. Un dernier paragraphe envisage les investigationsneuroendocriniennes permettant l'évaluation de la fonctionnalité des systèmes noradrénergique,dopaminergique et sérotoninergique, et de l'intérêt de l'utilisation de batteries de tests neuroendocriniens enpsychiatrie.


Pharmacoepidemiological Research on Outcomes of Therapeutics by a European ConsorTium IMI Work Package 5: Report 2:b:ii Benefit - Risk Wave 2 Case Study Report: Rosiglitazone Benefit-Risk Analysis Lawrence Phillips, Billy Amzal, Alex Asiimwe, Edmond Chan, Chen Chen, Diana Hughes, Juhaeri Juhaeri, Alain Micaleff, Shahrul Mt-Isa, Becky Noel, Susan Shepherd, Nan Wang On behalf of PROTECT Work Package 5 participants


circulaire relative à la protection des travailleurs contre la fumée de tabac 9 1. L'arrêté royal du 19 janvier 2005 relatif à la protection des travailleurs contre la fumée de tabac s'inscrit dans l'exécution des dispositions de la loi du 4 août 1996 relative au bien-être des travailleurs lors de l'exécution de leur travail.Par la présente circulaire, je souhaite rappeler, si besoin est, les mesures ainsi que la politique globale de restriction de l'usage du tabac dans les espaces de travail et les équipements sociaux que le Ministère de la Communauté française, en sa qualité d'employeur, est tenu de mettre en œuvre à partir du 1er janvier 2006.

Microsoft word - 16_1_ & __

Pan-Pacific Association of Applied Linguistics 16(1), 83-109 Convergence and Divergence in the Interpretation of QuranicPolysemy and Lexical Recurrence1 Jamal alQinai Kuwait University alQinai, J. (2012). Convergence and divergence in the interpretation of Quranicpolysemy and lexical recurrence.Journal of Pan-Pacific Association of Applied Linguistics, 16(1), 83-109. The question of using synonyms in translating the Quran is a thorny issue that led to both different interpretations and different translations of the holy text. No matter how accurate or professional a translator attempts to be, Quranic translation has always been fraught with inaccuracies and the skewing of sensitive theological, cultural and historical connotations owing to the peculiar mechanism of stress, semantico-syntactic ambiguity, prosodic and acoustic features, the mesh of special rhetorical texture and culture-bound references. Consequently, in most of the English interpretations of the Quran, cases of non-equivalence and untranslatability will be more frequent with plenty of scope for ambiguities, obscurities and fuzzy boundaries.The trend has been to accept exegetical translation based on commentary and explanation of the Quranic discourse. Since there is no uniform book of exegesis, translations are considered to be glosses or approximates for non-Arabic speaking Muslims. This study is mainly concerned with assessing the criteria and strategies used by different Quran translators in selecting synonyms to render Quranicpolysemous words. The linguistic- cultural context of the original polysemous ST word will be analyzed and compared with its TT near-synonyms.The study argues that in translating religious texts where synonyms are usually used to convey implicated meanings of ST polysemous words and where we seek to have the same effect on the Target Language receiver as that of the original, the use of functional ideational equivalence is given primacy over formal equivalence. Key Words: interpretation, polysems, synonyms, recurrence, exegesis

Storia di ordinaria sclerosi multipla - roberta

Corso di Perfezionamento Tecnologie per l'autonomia e l'integrazione sociale delle persone disabili Anno Accademico 1999/2000 Storia di ordinaria sclerosi multipla CANDIDATO: Bianca Tovo Abstract. Il caso di studio riguarda Roberta, 61 anni, che ha presentato i primi disturbi motori e sensitivi a 31anni e che dall'età di 43 anni si sposta esclusivamente in carrozzina. Ha conservato un discreto utilizzofunzionale dell'arto superiore sinistro.Ha uno spirito vivace e sensibile e ha affrontato la sua disabilità con coraggio e buon senso.Negli ultimi anni, anche in seguito ad una malattia del marito oltre che al proprio aggravamento motorio, haperso entusiasmo e ha rinunciato poco per volta alle attività che comportano fatica per lei e per chi l'assiste.Il progetto si propone di:• migliorare la stazione seduta in carrozzina


INVITED CLINICAL COMMENTARY Sexual wellbeing for people with chronic obstructive pulmonary disease: relevance and roles for physiotherapy William MM Levack PhD MHealSc(Rehabilitation) BPthyAssociate Dean Research & Postgraduate Studies; Senior Lecturer in Rehabilitation Rehabilitation Teaching and Research Unit, Department of Medicine, University of Otago Wellington, New Zealand

Pageflex server [document: z0282856_00001]

Benefits You Can Count On Prism EPO/Prism PPO/Blue View Vision Country Life LLC February 25, 2010 Dear Country Life employee, This is an important decision and this booklet is designed to help. Basically, it's a snapshot of the benef ts come with your Empire coverage. It summarizes what's available to you, what you get with each benef t your plans work. Of course, you should always refer to your evidence of coverage or medical policy for full plan details.


lo que tienes, Desarrollo y herramientas 4 cv / Adriana Torres Topaga 5 Vestido interactivo Proyectos realizados relacionados 6 ADRIANA TORRES TOPAGA lo que tienes, CACTUS" Vestido interactivo Introducción 1Descripción 2 Kostenaufstellung 5 cv / Adriana Torres Topaga 6 Proyectos realizados relacionados 7 1 IntroducciónEl "Muéstrame lo que tienes / CACTUS " es el resultado y la continuación de una serie de temas en la investigación relacionados con diferentes aspectos sobre clima y el cuerpo. Este proyecto se originó en el transcurso de mis estudios de Estrategias de espacio y de diseño, en la Universidad de Arte y Diseño Industrial de Linz bajo el tema "Furia de la naturaleza". el enfoque de mi trabajo es eel aspecto social del tiempo (clima social) y su representación.. De manera personal, surgió en la búsqueda de un espacio de investigación híbrido y dinámico en el en áreas aparentemente separadas como el diseño textil, la arquitectura, el diseño, sociología y

Cases 4-page layout c 04/07

Cases & Commentaries New Technology for Periodontal Treatment From the Editor Few novel therapies for the treatment of oral infections have been developed over the past decade. The current standard of care is to provide scaling and root planing, with or without antibiotics delivered eitherlocally or systemically. The introduction of photodisinfection to Canada and Europe in 2006 represented amilestone in new and innovative approaches to the treatment of oral infections.

Chloramphenicol revisited -- zero tolerance both problematic, ‘ever-moving'

Zero Tolerance Both Problematic, ‘Ever-Moving' are not as effective. In the Netherlands, a number of registered pharmaceuti- cal products incorporate chlorampheni- col, mainly in formulations used to treat eye infections. Chloramphenicol is also used intravenously against in- fections like meningitis. With regards to the presence of chlo- ramphenicol in the aquatic environ-

Validation of a brief questionnaire measuring positive mindset in patients with uveitis

Psychology, Community & Health 2182-438X Validation of a Brief Questionnaire Measuring Positive Mindset in PatientsWith Uveitis John A. Barry, Annie Folkard, William Ayliffe Please note that in the table in the Appendix, the fifth option for item 1 should be "Very happy", not "Very unhappy". [The author requested to add this note post-publication on 2014-04-08.]


Patient Insight: Patient journey reveals cost of Restless Legs Syndrome (RLS) Abstract Objective: The objective of the study was to quantify RLS misdiagnosis and delayed treatment in primary care and to examine the implications for the RLS patient journey and associated healthcare costs. Background: Restless legs syndrome (RLS) affects around 5-10% of adults in Western countries. However, awareness of the disease is relatively low: around 2 in 5 people in the UK have heard of it. Low awareness may be one reason it is misdiagnosed or diagnosed late. Late diagnosis and misdiagnosis has implications for the cost of the disorder to the health service. Method: An online questionnaire-based study of 157 adult patients with RLS from the UK was conducted in 2012. Results: The survey found it took an average of 7.53 visits for participants to receive an RLS diagnosis with some stating it took 20, 30 or more visits before a diagnosis was reached. For the majority (67%) it had taken over a year to be diagnosed with RLS. However, 23% of this group of respondents noted it had taken 10 years or more before they were diagnosed.

Microsoft word - programme.doc

Programme TUESDAY, 29 January 2008 Coffee and registration Welcome, by Preben Bach Holm, member of steering committee, Plant Biotech Denmark Session 1 – Products and Productivity (chair: Anna Haldrup) Keynote talkThe dependence of yield on photosynthesis: Opportunities for improvement,by Donald R. Ort, professor, University of Illinois, USA


Geophysical Journal International Geophys. J. Int. (2002) 148, 256–277 Morphological dating of cumulative reverse fault scarps: examplesfrom the Gurvan Bogd fault system, Mongolia S. Carretier,1,∗ J-F Ritz,1 J. Jackson2 and A. Bayasgalan21Laboratoire de G´eophysique Tectonique et S´edimentologie, CNRS-UMR, Universit´e Montpellier II, 4, Place Eug ene Bataillon, 34000 Montpellier, France.E-mail: scarret@dstu.univ-montp2.fr2Bullard Laboratories, Madingley Road, Cambridge, CB3 OEZ England


BRUNO TRENTIN DALLA GUERRA PARTIGIANA AL PARLAMENTO EUROPEO PERCORSI DI RICERCA La comparazione tra le esperienze nazionali, i partiti politici e i movimenti sindacali ha contribuito alla ricostruzione di una storiaunitaria della sinistra europea, con una certa attenzione perl'influenza del processo di integrazione sulla ridefinizione delleculture politiche e sindacali riguardanti la concezione dello Stato, ilgoverno dello sviluppo economico e il Welfare State1.

תהליך הערכת ביצועים משוב לעובדים על fy2007

Q11 Development and manufacture of Presented by Alex Weisman, Ph D Vice President R&D, Q11 Development and manufacture of Drug product: Chemagis overview • Founded in 1987, Chemagis is a subsidiary , Israel's second largest pharmaceutical conglomerate and part of the Perrigo Group. • Chemagis develops, produces and markets an extensive line of


Recommended Prostate-Specific Antigen Testing Intervals for the Detection of Curable Prostate Cancer H. Ballentine Carter, MD; Jonathan I. Epstein, MD; Daniel W. Chan, PhD; James L. Fozard, PhD; Jay D. Pearson, PhD Objective. p=m- Toevaluate prostate-specific antigen (PSA) testing intervals that curable cancer with less frequent test¬ maintain the detection of curable cancer and reduce unnecessary testing.


where can i find support and information? PSC Partners Seeking a Cure is a 501(c)3 nonprofit foundation that endeavors to find a cure for primary sclerosing cholangitis. for more information, or to help fund the cure: Please consider joining our mailing list at: Visit our website at: www.pscpartners.org An online PSC support group was established in 1998. This is a message board (forum) on Yahoo/Health, where PSC patients


Trouble obsessionnel compulsif Trouble obsessionnel compulsif Trouble obsessionnel-compulsif (TOC) Classification et ressources externes Un lavage de main répétitif est un symptôme du trouble obsessionnel-compulsif. Le trouble obsessionnel compulsif (abrégé TOCcaractérisé par l'apparition répétée de - produisant de l'inconfort, de l'inquiétude, de l'appréhension et/ou de la peur;


ORIGINAL CONTRIBUTION Fluoxetine After Weight Restorationin Anorexia NervosaA Randomized Controlled Trial B. Timothy Walsh, MD Context Antidepressant medication is frequently prescribed for patients with an- Allan S. Kaplan, MD, FRCPC orexia nervosa. Objective To determine whether fluoxetine can promote recovery and prolong time-


This article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues. Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party

01 problemstellungen und lösungsblätter 1-3 cublex

Cublex – Problemstellung 1 Drehe die acht miteinander beweglich verbundenen Würfelchen so, dass eine „Stange" entsteht, wie das untere Bild zeigt. Cublex – Problemstellung 2 Drehe die acht miteinander beweglich verbundenen Würfelchen so, dass das weisse Band im Würfel verschwindet. Cublex – Problemstellung 3 Drehe die acht miteinander beweglich verbundenen Würfelchen so, dass ein weisses Band durchgehend über den Würfel führt.


Eur. J. Biochem. 270, 3109–3121 (2003)  FEBS 2003 Gene regulation by tetracyclinesConstraints of resistance regulation in bacteria shape TetR for applicationin eukaryotes Christian Berens and Wolfgang Hillen Lehrstuhl fu¨r Mikrobiologie, Institut fu¨r Mikrobiologie, Biochemie und Genetik, Friedrich-Alexander Universita¨t Erlangen-Nu¨rnberg;Germany The Tet repressor protein (TetR) regulates transcription

Aplicaciones de la nanotecnología en la producción de leche

Aplicaciones de la nanotecnología en laproducción de leche El gran avance ocurrido en la instrumentación de laboratorio posibilitó el conocimiento y la comprensiónde fenómenos que ocurren en la nanoescala. En una partícula que tiene su tama?o reducido adimensiones inferiores a 1000 nm, los fenómenos físicos fácilmente visualizados en la escala métrica-como la gravedad, la fricción, la inercia y otros- tienen diminuida su importancia de acción sobre laspartículas y pasan a imperar otras fuerzas físicas, hasta entonces diminutas, como es el caso de la fuerzaeletrostática, de van der Waals, de las repulsiónes estéricas, del movimento browniano, y otras. De estemodo, una partícula puede presentar sus características aumentadas, o incluso ofrecer nuevascaracterísticas, cuando es comparada con su forma convencional. Como ejemplo se puede citar el caso delas nanopartículas de oro, que cuando poseen un diámetro medio inferior a 10 nm presentan coloraciónbermellón, y que cuando tienen su diámetro en dimensiones que oscilan entre 10 y 99 nm asumen unacoloración violácea en medio acuoso.Observaciones como esa se?alan como una gran posibilidad de progreso tecnológico el control de laorganización de átomos y moléculas, estimulando así en las últimas décadas firmes inversiones eninvestigación, que incluyen a la tecnología. Como resultado, se ha observado el desarrollo de productosinnovadores en la industria de la electrónica, de química fina, medicina, cosméticos, así como en el sectorde la automatización. Los avances en el conocimiento en estos sectores pueden ser fácilmente adaptadosa la industria de alimentos y así contribuir al desarrollo y a la mejora de los actuales equipos utilizadospara analizar fraudes, contaminantes químicos y biológicos, e incluso para el análisis de alimentos, loscuales pueden ser más rápidos, eficientes y económicos. En ese contexto, serán abordadas aplicacionesde la nanotecnología que pueden generar grandes beneficios para la cadena productiva de la leche.

5[alpha]-reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia

Int. J. Cancer: 120, 776–780 (2006)' 2006 Wiley-Liss, Inc. 5a-Reductase type 2 gene variant associations with prostate cancerrisk, circulating hormone levels and androgenetic alopecia Vanessa M. Hayes1,2*#, Gianluca Severi3,4*, Emma J.D. Padilla1, Howard A. Morris5, Wayne D. Tilley5,6,Melissa C. Southey7,8, Dallas R. English3,4, Robert L. Sutherland1,2, John L. Hopper4, Peter Boyle8 and Graham G. Giles3,41Cancer Research Program, Garvan Institute of Medical Research, St Vincent's Hospital, Sydney, Australia

Pontevedra 2

RAMÓN SOBRINO LORENZO-RUZA (1915-1959): EL TRAYECTO VOCACIONAL DE UN ARQUEÓLOGO Ángel Núñez Sobrino La culminación de la labor intelectual de Ramón en esta época, en el círculo de las relaciones atlán- Sobrino Lorenzo-Ruza fue la concesión de una ticas, apareciendo por ello en las Islas Británicas y beca de la "Fundación Juan March" en el extranje-


Philadelphia University Department of Athletics Compliance Program and Table of Contents Letter from the Director of Athletics Mission Statement Department of Athletics Directory Important Contacts on Campus Division of Student Life- Organizational Chart Section I – General Policies and Procedures Work

Microsoft powerpoint - 6. treatment of infected pressure sores

Treatment of Infected Pressure Ulcers Dr. Hasan Syed Ahmedullah Clinical Fellow Infectious Disease 2. Pressure Ulcer Classification 3. Strength of Evidence 4. Strength of Recommendation 5. Assessment of high risk individuals •Bacteria are present on all skin surfaces •When the primary defense provided by intact skin is lost, bacteria will


Case report A finding of live Fasciolopsis buski in an ileostomy opening Rakesh K. Mahajan1, Shalini Duggal2, Niraj K. Biswas3, Nandini Duggal1, Charoo Hans1 1Department of Microbiology, Dr Ram Manohar Lohia Hospital, New Delhi, India 2Department of Microbiology, Dr B. L. Kapur Memorial Hospital, Delhi, India 3Jhalawar Medical College, Jhalawar, Rajasthan, India Abstract A pair of live Fasciolopsis buski wriggled their way out through the ileostomy opening in a young adult male who had recently migrated to Delhi and had met with a road traffic accident. Finding this parasite in the national capital, a non endemic area for Fasciolopsiasis, prompted us to emphasize the importance of changes in the ecology, human demography, and human behaviour that may provide an environment conducive to their adaptability to the new geographical requirements. Awareness of Fasciolopsiasis, which is endemic in some regions of India, especially in rural settings, is an important issue because early diagnosis is essential. Hence, a surveillance mechanism among the migratory population to institute preventive interventions is necessary. Key words: endemic, intestinal trematode, plant-borne, migratory population J Infect Dev Ctries 2010; 4(6):401-403.

Newsletter dec 2010

Life Saving Organization Pakistan Myasthenic Welfare Organisation On behalf of the Muslim Aid Khalid Mehmood Zia Founder PMWO is handing over Platelets Kits to Chief Minister Punjab for the treatment of Dengue Fever Patients. "At this occasion Chief Minister Punjab Mian Muhammad Shahbaz Sharif appreciate the great contribution of Muslim Aid for Dengue Fever patients.

Microsoft word - investigatorsbrochurepsilo-final.doc

Psilocybin Investigator's Brochure March-April 2007 Psilocybin: Investigator's Brochure Table of Contents 1. Drug Substance and Formulation. 3 2. Pharmacological and toxicological effects . 3 Psilocybin and Psilocin Actions on Neurotransmitter Systems . 3 Overview. 3 Psilocybin or psilocin and 5HT2A and 5HT2C Receptors . 4 Psilocybin or Psilocin and other Serotonin Receptors . 4 Psilocybin or Psilocin and other Receptor Systems. 5 Human Neuropharmacological Studies . 6 Psilocybin and Gene Expression. 6


Classic Voice Verdi e Wagner - Feuilleton Classic Voice Verdi e Wagner - Feuilleton Il virus delle celebrazioni centenarie è la causa di questi dieci articoli, qui raccolti in un unico rac- conto che vorrebbe anche essere un racconto comune per Verdi e per Wagner. Che siano nati nello stesso anno non renderebbe di per sé legittimo che li si ac-


Nutritional Supplementation in Pregnancy It goes without saying that Nutrition in Pregnancy is vitally important for the developing fetus. Dietary requirements are increased substantially in a pregnant woman, and if she does not have enough in the way of proteins, vitamins and minerals in her own body stores, then her baby could be compromised. It has been clearly established that Pregnant women in Australia are not meeting their daily

Pii: s1064-1297(02)00230-4

Experimental and Clinical Psychopharmacology Copyright 2002 by the American Psychological Association, Inc. 2002, Vol. 10, No. 3, 162–183 Applying Laboratory Research: Drug Anticipation and the Treatment of Drug Addiction Shepard Siegel and Barbara M. C. Ramos McMaster University Basic research concerning drug tolerance and withdrawal may inform clinical practice, andvice versa. Three areas that integrate the work of the laboratory and the clinic are discussed:(a) drug overdose, (b) cue exposure treatment of addiction, and (c) pharmacological treatmentof withdrawal symptoms. The areas are related in that they indicate the contribution ofdrug-paired cues to the effects of addictive drugs and the role of Pavlovian conditioning ofdrug effects in drug tolerance and withdrawal symptoms.

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